Growth Inhibitory Activity of Acronychia acidula F. Muell. Fruit Extracts Towards Malodour-forming Bacteria

groupview

Abstract
Pharmacognosy Communications,2020,10,2,95-101.
Published:April 2020
Type:Original Article

Growth Inhibitory Activity of Acronychia acidula F. Muell. Fruit Extracts Towards Malodour-forming Bacteria

Mitchell Henry Wright1, Aiden Wood2, Anthony Carlson Greene2, Ian Edwin Cock1,2,3,*

1Leviathan Biosciences, Brisbane, Queensland, AUSTRALIA.

2School of Environment and Science, Griffith University, Brisbane, Queensland, AUSTRALIA.

3Environmental Futures Research Institute, Nathan Campus, Griffith University, Brisbane, Queensland, AUSTRALIA.

Abstract:

Introduction: Acronychia acidula F. Muell. (lemon aspen, pigeon berry) has been previously recognized for its antimicrobial properties against a broad panel of pathogenic bacteria. This study assessed the effectiveness of A. acidula as an inhibitory agent against bacteria associated with malodour formation. Methodology: A. acidula fruit extracts were prepared using methanol or water as the extraction solvent. Growth inhibition and minimal inhibitory concentrations were determined against C. jeikeium, P. acnes and B. linens through disc diffusion assays. MIC values were quantified to evaluate their efficacies as antimicrobials. Toxicity of each extract was determined using the Artemia franciscana nauplii bioassay. Results: A. acidula aqueous fruit extracts inhibited the growth of B. linens (MIC = 1258 μg/mL), C. jeikeium (MIC = 1630 μg/mL) and P. acnes (MIC = 1455 μg/mL) in the disc diffusion assay. Similarly, the methanolic fruit extracts inhibited the growth of B. linens (MIC = 2608 μg/mL) and C. jeikeium (MIC = 3044 μg/mL), although no growth inhibition of P. acnes was observed. Both aqueous and methanolic A. acidula extracts were nontoxic towards Artemia nauplii (LC50 values of 1872 μg/mL and 1500 μg/mL). Conclusion: A. acidula fruit extracts were non-toxic and also displayed moderate growth inhibitory bioactivity against B. linens, C. jeikeium and P. acnes, highlighting their potential as additives to deodorants.

Founded:  In 2004, as the PHCOG.NET – a non-profit private organization dedicated to Natural Products Research leading to develop promising drugs. Our main mission is to make information on herbal drug research readily available in different formats to suit the individual needs.

Pharmacognosy Communications [Phcog Commn.] is a new quarterly journal published by Phcog.Net. It is a peer reviewed journal aiming to publish high quality original research articles, methods, techniques and evaluation reports, critical reviews, short communications, commentaries and editorials of all aspects of medicinal plant research. The journal is aimed at a broad readership, publishing articles on all aspects of pharmacognosy, and related fields. The journal aims to increase understanding of pharmacognosy as well as to direct and foster further research through the dissemination of scientific information by the  publication of manuscripts. The submission of original contributions in all areas of pharmacognosy are welcome.

The journal aims to cater the latest outstanding developments in the field of pharmacognosy and natural products and drug design covering but not limited to the following topics:

  • Pharmacognosy and pharmacognistic investigations
  • Research based ethnopharmacological evaluations
  • Biological evaluation of crude extracts, essential oils and pure isolates
  • Natural product discovery and evaluation
  • Mechanistic studies
  • Method and technique development and evaluation
  • Isolation, identification and structural elucidation of natural products
  • Synthesis and transformation studies

Distinctions:  The most widely read, cited, and known Pharmacognosy Communications and website is well browsed with all the articles published. More than 20,000 readers in nearly every country in the world each month

Aim and Scope | Editorial Board | Indexed & Abstracted | Instruction to Authors | Manuscript Submission & Charges

Subjects Covered : Natural Products, Pharmacognosy, Phytochemistry, Marine Pharmacognosy and Zoo Pharmacognosy
ISSN :2249-0159 (Print) ; 2249-0167 (Online) Frequency : Quarterly Rapid at a time publication (4 issues/year)

Indexed and Abstracted in : Chemical Abstracts, Excerpta Medica / EMBASE, Google Scholar, CABI Full Text, Ulrich’s International Periodical Directory, ProQuest, Journalseek & Genamics, PhcogBase, EBSCOHost, Academic Search Complete, Open J-Gate, SciACCESS.
Rapid publication: Average time from submission to first decision is 30 days and from acceptance to In Press online  publication is 45 days.
Open Access Journal: Phcog Commn. is an open access journal, which allows authors to fund their article to be open access from publication.