Facebook Twitter Instagram
    • Home
    • About Journal
      • Aim and Scope
      • Editorial Board
      • Indexing Info
      • Contact Us
    • Browse Issues
      • Articles in Press
      • Current Issue
      • Past Issues
    • For Authors
      • Instructions to Authors
      • Article Processing Charges
      • Submit your article
      • Downloads
    Facebook Twitter Instagram
    Pharmacognosy Communications
    • Home
    • About Journal
      • Aim and Scope
      • Editorial Board
      • Indexing Info
      • Contact Us
    • Browse Issues
      • Articles in Press
      • Current Issue
      • Past Issues
    • For Authors
      • Instructions to Authors
      • Article Processing Charges
      • Submit your article
      • Downloads
    Pharmacognosy Communications
    retyeyutreu
    Original Article

    Growth inhibitory properties of Backhousia myrtifolia Hook. & Harv. and Syzygium anisatum (Vickery) Craven & Biffen extracts against a panel of pathogenic bacteria

    wadmin2By wadmin2August 6, 2016Updated:August 11, 2021No Comments2 Mins Read
    Facebook Twitter Pinterest LinkedIn Tumblr WhatsApp Email
    Share
    Facebook Twitter LinkedIn WhatsApp Pinterest Email

    Krystal Bryant1 and Ian Edwin Cock1,2*
    1School of Natural Sciences, Nathan Campus, Griffith University, 170 Kessels Rd, Nathan, Brisbane, Queensland 4111, AUSTRALIA.
    2Environmental Futures Centre, Nathan Campus, Griffith University, 170 Kessels Rd, Nathan, Brisbane, Queensland 4111, AUSTRALIA.

    Pharmacognosy Communications,2016,6,4,194-203.
    DOI:10.5530/pc.2016.4.2
    Published: August 2016
    Type: Original Article

    ABSTRACT

    Introduction: B. myrtifolia and S. anisatum are native Australian trees with uses as traditional medicines and bushfoods. Essential oils produced from leaves of these species have reputed antiseptic properties. Despite this, B. myrtifolia and S. anisatum leaf solvent extractions have not been rigorously examined for antibacterial properties against many pathogens. Methods: The antimicrobial activity of aqueous and methanolic leaf extracts of B. myrtifolia and S. anisatum was investigated by disc diffusion and growth time course assays against a panel of pathogenic bacteria. The growth inhibitory activity was quantified by MIC determination. Toxicity was determined using the Artemia franciscana nauplii bioassay. Results: Methanolic and aqueous B. myrtifolia and S. anisatum leaf extracts inhibited the growth of a wide range of bacterial species. Growth of both gram positive and gram negative bacteria was inhibited the B. myrtifolia and S. anisatum extracts to approximately the same extent. In general, S. anisatum extracts were more potent inhibitors of bacterial growth than were the B. myrtifolia extracts, and (with some noteable exceptions) the methanolic extracts were generally more potent than the aqueous extracts. The B. myrtifolia and S. anisatum extracts were particularly potent inhibitors of P. mirabilis growth, with MIC values as low as 105 μg/mL (aqueous S. anisatum extract). The antibacterial activity of the methanolic B. myrtifolia and S. anisatum extracts were further investigated by growth time course assays which showed significant growth inhibition in cultures of E. coli, K. pneumpniae and P. mirabilis within 1 h of exposure. All extracts were determined to be nontoxic in the Artemia franciscana nauplii bioassay, indicating their safety for internal use as well as for topical uses. Conclusions: The lack of toxicity of the B. myrtifolia and S. anisatum extracts and their growth inhibitory bioactivity against a panel of pathogenic bacteria partially validate Australian Aboriginal usage of these species as antiseptic agent and indicate their potential in the development of antiseptic agents.

    Key words: Backhousia myrtifolia, Syzygium anisatum, Cinnamon myrtle, Anise myrtle, Australian plants, Antibacterial activity, Medicinal plants.

    Download PDF
    Share. Facebook Twitter Pinterest LinkedIn Tumblr WhatsApp Email
    About Journal
    About Journal

    Pharmacognosy Communications [Phcog Commn.] is a quarterly journal published by Phcog.Net. It is a peer reviewed journal aiming to publish high quality original research articles, methods, techniques and evaluation reports, critical reviews, short communications, commentaries and editorials of all aspects of medicinal plant research. The journal is aimed at a broad readership, publishing articles on all aspects of pharmacognosy, and related fields. The journal aims to increase understanding of pharmacognosy as well as to direct and foster further research through the dissemination of scientific information by the publication of manuscripts. The submission of original contributions in all areas of pharmacognosy are welcome.
    Indexed and Abstracted in : Chemical Abstracts, Excerpta Medica / EMBASE, Google Scholar, CABI Full Text, Ulrich’s International Periodical Directory, ProQuest, Journalseek & Genamics, PhcogBase, EBSCOHost, Academic Search Complete, Open J-Gate, SciACCESS.
    Rapid publication: Average time from submission to first decision is 30 days and from acceptance to In Press online publication is 45 days.
    Open Access Journal: Phcog Commn. is an open access journal, which allows authors to fund their article to be open access from publication.

    © 2025 Pharmacognosy Communications. Maintained by Manuscript TechnoMedia LLP.

    Type above and press Enter to search. Press Esc to cancel.

    Scroll Up