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    Pharmacognosy Communications
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    Pharmacognosy Communications
    retyeyutreu
    Original Article

    Kunzea ambigua (Sm.) Druce and Kunzea flavescens C.T. White and W.D. Francis Essential Oils Inhibit the Growth of Some Bacterial Triggers of Inflammatory Diseases

    Web AdminBy Web AdminApril 1, 2021Updated:August 4, 2021No Comments2 Mins Read
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    Célia Barillot1,2, Ian Edwin Cock1,3,*

    1Environmental Futures Research Institute, Griffith University, Brisbane, AUSTRALIA.

    2School of Biology, Ecole de Biologie Industrielle (EBI), Cergy, FRANCE.

    3School of Environment and Science, Griffith University, Brisbane, AUSTRALIA.

    Pharmacognosy Communications,2021,11,2,81-87.
    DOI:10.5530/pc.2021.2.17
    Published:April 2021
    Type:Original Article

    ABSTRACT

    Introduction: Kunzea ambigua (Sm.) Druce and Kunzea flavescens C.T. White and W.D. Francis are endemic Australian plants. Decoctions, infusions and essential oils produced from the leaves were used traditionally to treat a variety of bacterial diseases. Despite this, these species have not been rigorously examined for antibacterial properties against many pathogens. Methods: The antimicrobial activity of K. ambigua and K. flavescens essential oils and a K. ambigua hydrosol was investigated by disc diffusion and liquid dilution MIC assays against a panel of pathogenic bacteria. Toxicity was determined using the Artemia franciscana nauplii bioassay. Results: K. ambigua and K. flavescens essential oils displayed noteworthy growth inhibitory activity against A. baylyi, K. pneumonia, P. mirabilis and P. aeruginosa (MIC values substantially <1000μg/mL). Indeed, MIC values as low as 33μg/mL were noted against P. aeruginosa. Noteworthy growth inhibitory activity was also noted for the K. ambigua hydrosol against A. baylyi and P. aeruginosa. All extracts were determined to be non-toxic in the Artemia franciscana nauplii bioassay, indicating their safety for internal use as well as for topical uses. Conclusion: The lack of toxicity of the Kunzea spp. extracts and their growth inhibitory bioactivity against a panel of pathogenic bacteria partially validate the traditional usage of these species to treat bacterial diseases and indicate their potential in the development of antiseptic agents.

    Key words: Ankylosing spondylitis, Antibacterial activity, Australian plants, Multiple sclerosis, Myrtaceae, rheumatoid arthritis, Tick bush, White Kunzea
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    About Journal
    About Journal

    Pharmacognosy Communications [Phcog Commn.] is a quarterly journal published by Phcog.Net. It is a peer reviewed journal aiming to publish high quality original research articles, methods, techniques and evaluation reports, critical reviews, short communications, commentaries and editorials of all aspects of medicinal plant research. The journal is aimed at a broad readership, publishing articles on all aspects of pharmacognosy, and related fields. The journal aims to increase understanding of pharmacognosy as well as to direct and foster further research through the dissemination of scientific information by the publication of manuscripts. The submission of original contributions in all areas of pharmacognosy are welcome.
    Indexed and Abstracted in : Chemical Abstracts, Excerpta Medica / EMBASE, Google Scholar, CABI Full Text, Ulrich’s International Periodical Directory, ProQuest, Journalseek & Genamics, PhcogBase, EBSCOHost, Academic Search Complete, Open J-Gate, SciACCESS.
    Rapid publication: Average time from submission to first decision is 30 days and from acceptance to In Press online publication is 45 days.
    Open Access Journal: Phcog Commn. is an open access journal, which allows authors to fund their article to be open access from publication.

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