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    Pharmacognosy Communications
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    Pharmacognosy Communications
    retyeyutreu
    Short Communication

    Antimicrobial activity of Thai medicinal plants against beverage spoilage microorganisms and their potential in retarding Alzheimer’s disease progression

    wadmin2By wadmin2May 26, 2014Updated:August 10, 2021No Comments1 Min Read
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    Suree Nanasombat*, Thanawan Bubpasawana, Nunthaporn Tamaputa and Yuwapa Srimakhana
    aDepartment of Biology, Faculty of Science, King Mongkut’s Institute of Technology Ladkrabang, Bangkok 10520, Thailand.

    Pharmacognosy Communications,2014,4,3,77-87.
    DOI:10.5530/pc.2014.3.8
    Published:May 2014
    Type:Short Communication

    ABSTRACT

    Thai medicinal plants (34 crude methanolic extracts) were tested for their antimicrobial activities, antiacetylcholinesterase and antioxidant activities, total phenolic and flavonoid contents. Acorus calamus, Cassia alata, Crocus sativus, Nymphaea lotus and Phyllanthus emblica extracts showed strong antimicrobial activity against spoilage yeasts, lactic acid bacteria and acetic acid bacteria tested. Most susceptible yeast strains were Rhodotorula glutinis and Schizosaccharomyces pombe. Kaempferia parviflora, Nelumbo nucifera, Rauvolfia serpentina and Centella asiatica extracts exhibited strong acetylcholinesterase inhibitory activity (more than 70 % inhibition). Terminalia chebula, Cinnamomum bejolghota, Uncaria gambir and P. emblica extracts had the strongest antioxidant activity, EC50 of 387.23 – 490.47 μg extract/mg 2, 2-diphenyl-1-picrylhydrazyl (DPPH) by DPPH radical scavenging activity method and reducing capacity of 656.19 – 774.41 mmol Fe(II)/g by ferric reducing antioxidant power (FRAP) method. U. gambir extract had the highest total phenolic and flavonoid contents (771.59 mg gallic acid equivalents (GAE)/g and 2,292.43 mg quercetin equivalents (QE)/g, respectively).

    Keywords: Anti-acetylcholinesterase activity, antioxidant activity, phenolics, flavonoids, medicinal plants.

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    About Journal
    About Journal

    Pharmacognosy Communications [Phcog Commn.] is a quarterly journal published by Phcog.Net. It is a peer reviewed journal aiming to publish high quality original research articles, methods, techniques and evaluation reports, critical reviews, short communications, commentaries and editorials of all aspects of medicinal plant research. The journal is aimed at a broad readership, publishing articles on all aspects of pharmacognosy, and related fields. The journal aims to increase understanding of pharmacognosy as well as to direct and foster further research through the dissemination of scientific information by the publication of manuscripts. The submission of original contributions in all areas of pharmacognosy are welcome.
    Indexed and Abstracted in : Chemical Abstracts, Excerpta Medica / EMBASE, Google Scholar, CABI Full Text, Ulrich’s International Periodical Directory, ProQuest, Journalseek & Genamics, PhcogBase, EBSCOHost, Academic Search Complete, Open J-Gate, SciACCESS.
    Rapid publication: Average time from submission to first decision is 30 days and from acceptance to In Press online publication is 45 days.
    Open Access Journal: Phcog Commn. is an open access journal, which allows authors to fund their article to be open access from publication.

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