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    Pharmacognosy Communications
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    Pharmacognosy Communications
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    Research Letter

    Antimicrobial activity of an Algerian medicinal plant: Carthamus caeruleus L.

    wadmin2By wadmin2December 2, 2013Updated:August 10, 2021No Comments2 Mins Read
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    Saffidine Karimaa, Sahli Faridaa and Zerroug Mohamed Mihoubb
    aDepartment of Medicine, Faculty of Medicine, University Ferhat Abbas of Sétif, ALGERIA.
    bDepartment of Microbiology, Faculty of Natural and Live Sciences, University Ferhat Abbas of Sétif, ALGERIA.

    Pharmacognosy Communications,2013,3,4,71-76.
    DOI:10.5530/pc.2013.4.10
    Published:December 2013
    Type:Research Letter

    ABSTRACT

    Background: Medicinal plants constitute a source of bioactive substances to treat chronic as well as infectious diseases in many countries of the world. A wide range of natural antimicrobial agents can either inhibit the growth of microorganisms or kill them and represent a good alternative to chemical drugs for treatment of various infectious diseases to face the phenomena of germ resistance. Methods: In our study, we have used plants of the genus Carthamus, which are widely distributed in the Mediterranean region and have been traditionally used to treat skin diseases and burns. Our experiments were carried on the roots and leaves of a Carthamus species growing in Sétif area in the North-East of Algeria, in order to evaluate its antimicrobial activity. Results: Our results showed potent activity of root and leaf extracts in vitro against Gram-negative and Gram-positive bacteria strains as well as against pathogenic fungus. Variable antimicrobial effects of different extracts have been obtained against the tested microorganisms. For root extracts, high inhibition zone of 25 mm was exhibited on Candida albicans, 20 mm against Staphylococcus aureus and Bacillus cereus, and 15 mm on Acinetobacter bowie. Moderate activity of 12 mm and 11 mm was obtained for pathogenic plant fungi (Aschochyta rabiei and Fusarium Var coerileum) and lowest activity of 8.3 mm was obtained for Fusarium oxysporum albidinis. Leaf extracts were only effective against Acinetobacter bowii and Staphylococcus aureus with inhibition zones of 18 and 20 mm respectively. The root extracts were more active than the leave extracts against the tested microorganisms.

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    About Journal
    About Journal

    Pharmacognosy Communications [Phcog Commn.] is a quarterly journal published by Phcog.Net. It is a peer reviewed journal aiming to publish high quality original research articles, methods, techniques and evaluation reports, critical reviews, short communications, commentaries and editorials of all aspects of medicinal plant research. The journal is aimed at a broad readership, publishing articles on all aspects of pharmacognosy, and related fields. The journal aims to increase understanding of pharmacognosy as well as to direct and foster further research through the dissemination of scientific information by the publication of manuscripts. The submission of original contributions in all areas of pharmacognosy are welcome.
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    Open Access Journal: Phcog Commn. is an open access journal, which allows authors to fund their article to be open access from publication.

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