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    Pharmacognosy Communications
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    Pharmacognosy Communications
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    Original Article

    Essential Oil and Bioactivity of the Ziziphora canescens Benth. Growing Wild in Lebanon

    wadmin2By wadmin2July 31, 2015Updated:August 10, 2021No Comments2 Mins Read
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    Chantal Abou Jaoudeh1, Safa Baydoun2 and Nelly Arnold1*
    1Faculté des Sciences Agronomiques, Université Saint Esprit, Kaslik, Lebanon.
    2Research Center for Environment and Development, Beirut Arab University, Lebanon.

    Pharmacognosy Communications,2015,5,4,265-269.
    DOI:10.5530/pc.2015.4.9
    Published:July 2015
    Type:Original Article

    ABSTRACT

    Introduction: Ziziphora canescens Benth. (Lamiaceae) is a medicinal plant widespread species in Mediterranean countries. This study was designed to evaluate the chemical composition and in vitro antimicrobial activities of this species growing wild in Lebanon. Material and Methods: The essential oil of the dry aerial flowering parts of Z. canescens from the Lebanese side of Mount Hermon (1843 m altitude above sea level) was obtained by hydrodistillation. The GC-MS analysis of the obtained essential oil was performed. The antimicrobial activity of the oil was tested against six certified bacteria and two certified fungi using disc-diffusion method and determination of the minimal inhibitory concentration (MIC) by agar dilution method. Results and Discussion: The yield of essential oil was 0.6ml/100g dry weight. GC -MS analysis revealed twenty eight components representing 93.0% of the total essential oil. Oxygenated monoterpenes (80.6%) were the predominant fraction of the essential oil with pulegone (39.2%), eucarvone (12.6%), D-menthone (10.3%), 3-cyclohexen-1-one, 2-isopropyl- 5-methyl- (9.1%). The oil exhibited a broad-spectrum of antimicrobial activity against the tested pathogenic microorganisms. The yeast Candida albicans and Salmonella enteritidis were the most susceptible with growth inhibition zones of 40.5 ± 0.7 mm and 29.0 ± 0.7 mm, respectively, and MIC values of 5μg/ml. These values were similar to those of pulegone and each the antibiotics Nystatine and Amikacine, respectively whilst, the fungus Trichophyton mentagrophytes was the most resistant. Conclusion: The results of this study support the notion that the essential oil of Z. canescens Benth. may be important as a pharmaceutical and food preservative.

    Key words: Antimicrobial activities, Chemical composition of essential oil, Eurcarvone, Pulegone, Ziziphora canescens Benth.

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    About Journal
    About Journal

    Pharmacognosy Communications [Phcog Commn.] is a quarterly journal published by Phcog.Net. It is a peer reviewed journal aiming to publish high quality original research articles, methods, techniques and evaluation reports, critical reviews, short communications, commentaries and editorials of all aspects of medicinal plant research. The journal is aimed at a broad readership, publishing articles on all aspects of pharmacognosy, and related fields. The journal aims to increase understanding of pharmacognosy as well as to direct and foster further research through the dissemination of scientific information by the publication of manuscripts. The submission of original contributions in all areas of pharmacognosy are welcome.
    Indexed and Abstracted in : Chemical Abstracts, Excerpta Medica / EMBASE, Google Scholar, CABI Full Text, Ulrich’s International Periodical Directory, ProQuest, Journalseek & Genamics, PhcogBase, EBSCOHost, Academic Search Complete, Open J-Gate, SciACCESS.
    Rapid publication: Average time from submission to first decision is 30 days and from acceptance to In Press online publication is 45 days.
    Open Access Journal: Phcog Commn. is an open access journal, which allows authors to fund their article to be open access from publication.

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