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    Pharmacognosy Communications
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    Pharmacognosy Communications
    retyeyutreu
    The Janus Corner

    The Janus Corner

    wadmin2By wadmin2January 5, 2016Updated:August 11, 2021No Comments2 Mins Read
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    Ian Edwin Cock1,2*
    1School of Natural Sciences, Nathan Campus, Griffith University, 170 Kessels Rd, Nathan, Brisbane, Queensland 4111, AUSTRALIA.
    2Environmental Futures Centre, Nathan Campus, Griffith University, 170 Kessels Rd, Nathan, Brisbane, Queensland 4111, AUSTRALIA.

    Pharmacognosy Communications,2016,6,2,112-114.
    Published: January 2016
    Type: The Janus Corner

    ABSTRACT

    Giardiasis (caused by protozoal parasites of the genus Giardia) is a crippling gastrointestinal disease. A recent report by researchers at Griffith University, Australia has reported that extracts prepared from Terminalia ferdinandiana (Kakadu plum) fruits are effective in the inhibition of growth of Giardia duodenalis trophozoites.1 Fruit extracts prepared with water were particularly effective inhibitors but anti-Giardial activity was also detected in methanolic, ethyl acetate and chloroform extracts. Through these results, the authors identified several compounds likely attributing to the inhibitory activity of G. duodenalis. This study offers an innovative approach to the prevention of giardiasis and further highlights the significance of Kakadu plum in the treatment and prevention of microbially caused diseases. This is a significant finding in the treatment of giardiasis as currently there are limited options from a chemotherapeutic standpoint. The ability of the aqueous fruit extract to act as a potent inhibitor offers a natural means of treatment as preparation can be achieved without the use of a chemical solvent. Furthermore, ingestion of Kakadu plum as a natural food source may offer a means of giardiasis prevention. Finally, there have been numerous reports of G. duodenalis resistances to metronidazole (the gold standard) and other drugs2 and this paper offers an additional means of treatment. The authors suggest a ground-breaking approach to the management of giardiasis as well as present Kakadu plum as an excellent natural resource for drug development. Read more…

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    About Journal
    About Journal

    Pharmacognosy Communications [Phcog Commn.] is a quarterly journal published by Phcog.Net. It is a peer reviewed journal aiming to publish high quality original research articles, methods, techniques and evaluation reports, critical reviews, short communications, commentaries and editorials of all aspects of medicinal plant research. The journal is aimed at a broad readership, publishing articles on all aspects of pharmacognosy, and related fields. The journal aims to increase understanding of pharmacognosy as well as to direct and foster further research through the dissemination of scientific information by the publication of manuscripts. The submission of original contributions in all areas of pharmacognosy are welcome.
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