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    Pharmacognosy Communications
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    Pharmacognosy Communications
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    Original Article

    Assessment of Coercive Stress on the Behavioral, Exploratory and Metabolic Response in the Wistar Rats

    Web AdminBy Web AdminApril 10, 2022Updated:April 12, 2022No Comments1 Min Read
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    Chahira Retem, Samir Djemli*, Fella Chebbah, Ines Refes, Amina Djouini, Bairi Abdelmadjid
    Department of Biology, Applied Neuroendocrinology Laboratory, Faculty of Sciences, Badji Mokhtar Annaba University, Annaba, ALGERIA
    DOI: 10.5530/pc.2022.2.12

    ABSTRACT

    Background: Stress is a strain on our mental and physical functions caused by various aversive and harmful events, inducing adaptive biological responses. However, if a stressful situation is too intense or persists over time, its repercussions on the individual become pathogenic. Stress also affects the animal world and represents an ethical and economic problem for farm animals and their welfare. Aim: The aim of our study is to evaluate the effect of restraint stress and its consequences. Materials and Methods: Twenty-four male and female Rattus rattus rats of the Wistar strain were exposed to two daily sessions of restraint stress over a period of 5 days. Results: Following this, locomotors exploratory anxiety-like behaviors were quantified in the elevated plus maze test and the open field test, and compared to control groups. Conclusion: The existence of a correlation between the behavioral consequences and the variation of the lipid profile following the induction of restraint stress was noted.

    Key words: Stress, Anxiety, Lipid profile, Locomotion, Elevated plus maze.

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    About Journal
    About Journal

    Pharmacognosy Communications [Phcog Commn.] is a quarterly journal published by Phcog.Net. It is a peer reviewed journal aiming to publish high quality original research articles, methods, techniques and evaluation reports, critical reviews, short communications, commentaries and editorials of all aspects of medicinal plant research. The journal is aimed at a broad readership, publishing articles on all aspects of pharmacognosy, and related fields. The journal aims to increase understanding of pharmacognosy as well as to direct and foster further research through the dissemination of scientific information by the publication of manuscripts. The submission of original contributions in all areas of pharmacognosy are welcome.
    Indexed and Abstracted in : Chemical Abstracts, Excerpta Medica / EMBASE, Google Scholar, CABI Full Text, Ulrich’s International Periodical Directory, ProQuest, Journalseek & Genamics, PhcogBase, EBSCOHost, Academic Search Complete, Open J-Gate, SciACCESS.
    Rapid publication: Average time from submission to first decision is 30 days and from acceptance to In Press online publication is 45 days.
    Open Access Journal: Phcog Commn. is an open access journal, which allows authors to fund their article to be open access from publication.

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