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    Pharmacognosy Communications
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    Pharmacognosy Communications
    retyeyutreu
    Original Article

    Citrus australasica F. Muell. Leaf Extracts are Ineffective Inhibitors of the Growth of a Panel of Bacterial Pathogens

    Web AdminBy Web AdminOctober 12, 2022Updated:July 5, 2024No Comments2 Mins Read
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    Lindy Mpala1, Getmore Chikowe1, Ian E Cock1,2,*
    1School of Environment and Science, Nathan Campus, Griffith University, Brisbane, Queensland, AUSTRALIA.
    2Centre for Planetary Health and Food Security, Griffith University, Brisbane, Queensland, AUSTRALIA.
    DOI: 10.5530/pc.2022.4.26

    ABSTRACT

    Introduction: Closely related plant species often share similar secondary metabolites and bioactivities and are therefore good targets for bioactivity testing when one or more species within a genus are known to possess therapeutic properties. The genus Citrus has a long history of ethnobotanbical usage in many areas of the world. Many species are known to have therapeutic properties, several species of which have well established antibacterial bioactivities. Materials and Methods: The ability of Citrus australasica F. Muell. leaf extracts to inhibit the growth of a panel of bacterial pathogens was investigated by disc diffusion assay. Toxicity was examined using the Artemia franciscana nauplii bioassay. Results: The C. australasica methanolic and aqueous extracts were ineffective at inhibiting the growth of gram-positive and gram-negative panels of bacteria and were non-toxic in the Artemia lethality assay following 24 hr exposure. Conclusion: Despite its close taxonomic relationship with several bioactive Citrus spp. with antibacterial activity, C. australasica leaf extracts were ineffective bacterial growth inhibitors. However, these extracts may have other therapeutic properties and testing against protozoa, fungi, virus and tumour cells is required.

    Keywords: Rutaceae, Finger lime, Caviar lime, Pharmacognosy, Traditional medicine, Medicinal plants, Toxicity.

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    About Journal

    Pharmacognosy Communications [Phcog Commn.] is a quarterly journal published by Phcog.Net. It is a peer reviewed journal aiming to publish high quality original research articles, methods, techniques and evaluation reports, critical reviews, short communications, commentaries and editorials of all aspects of medicinal plant research. The journal is aimed at a broad readership, publishing articles on all aspects of pharmacognosy, and related fields. The journal aims to increase understanding of pharmacognosy as well as to direct and foster further research through the dissemination of scientific information by the publication of manuscripts. The submission of original contributions in all areas of pharmacognosy are welcome.
    Indexed and Abstracted in : Chemical Abstracts, Excerpta Medica / EMBASE, Google Scholar, CABI Full Text, Ulrich’s International Periodical Directory, ProQuest, Journalseek & Genamics, PhcogBase, EBSCOHost, Academic Search Complete, Open J-Gate, SciACCESS.
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    Open Access Journal: Phcog Commn. is an open access journal, which allows authors to fund their article to be open access from publication.

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