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    Pharmacognosy Communications
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    Pharmacognosy Communications
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    Review Article

    Potentials of Endophytic Fungus Untapped, including Novel Bioactive Compounds

    Web AdminBy Web AdminMay 5, 2023Updated:May 5, 2023No Comments2 Mins Read
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    Kavya Shree Basappa1, Sri Raghava2, Sharan Umesha1,*

    1Department of Biotechnology, University of Mysore, Manasagangotri, Mysore, Karnataka, INDIA

    2Department of Biotechnology, Karnataka State Open University, Muktagangotri, Mysore, Karnataka, INDIA

    DOI : 10.5530/pc.2023.2.10

    ABSTRACT

    Endophytic fungi have attracted a lot of attention over the past century because of their capacity to produce novel bioactive chemicals with a variety of biological properties, which are then used for medical, pharmacological, and agricultural purposes. Endophytic fungi maintain the physiological and ecological characteristics of the host plant by living inside the plant tissues without causing any disease symptoms. Innovative lead chemicals created by endophytic fungus, such paclitaxel and penicillin, cleared the path for the investigation of new bioactive compounds for industrial application. These bioactive substances are classified as alkaloids, peptides, steroids, terpenoids, phenols, quinones, phenols, and flavonoids, among other structural groupings. The current review is concerned with the importance of endophytic fungi in creating novel bioactive substances with a range of biological properties, such as antibacterial, antiviral, antifungal, antiprotozoal, antiparasitic, antioxidant, immunosuppressive, and anticancer effects. The antibacterial and antiviral properties of endophyte-produced metabolites against human infections are highlighted in this review. It also emphasizes how important it is to use these substances as possible cures for major, life-threatening infectious diseases. The need to intensify the search for new, more effective and affordable antimicrobial medications is motivated by the fact that various results have suggested that these bioactive chemicals may considerably contribute to the fight against resistant human and plant infections.

    Keywords: Endophytic fungi, Paclitaxel, Penicillin, Bioactive compounds, Antimicrobial drugs.

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    About Journal
    About Journal

    Pharmacognosy Communications [Phcog Commn.] is a quarterly journal published by Phcog.Net. It is a peer reviewed journal aiming to publish high quality original research articles, methods, techniques and evaluation reports, critical reviews, short communications, commentaries and editorials of all aspects of medicinal plant research. The journal is aimed at a broad readership, publishing articles on all aspects of pharmacognosy, and related fields. The journal aims to increase understanding of pharmacognosy as well as to direct and foster further research through the dissemination of scientific information by the publication of manuscripts. The submission of original contributions in all areas of pharmacognosy are welcome.
    Indexed and Abstracted in : Chemical Abstracts, Excerpta Medica / EMBASE, Google Scholar, CABI Full Text, Ulrich’s International Periodical Directory, ProQuest, Journalseek & Genamics, PhcogBase, EBSCOHost, Academic Search Complete, Open J-Gate, SciACCESS.
    Rapid publication: Average time from submission to first decision is 30 days and from acceptance to In Press online publication is 45 days.
    Open Access Journal: Phcog Commn. is an open access journal, which allows authors to fund their article to be open access from publication.

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