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    Pharmacognosy Communications
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    Pharmacognosy Communications
    retyeyutreu
    Original Article

    Jacksonia scoparia R. Br. Leaf Extracts Lack Antibacterial Activity and are Non-toxic in vitro

    Web AdminBy Web AdminMay 5, 2023Updated:May 5, 2023No Comments2 Mins Read
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    Lindiwe Nomathemba Mpala1, Getmore Rumbudzai Chikowe1, Ian E. Cock1, 2,*

    1School of Environment and Science, Nathan Campus, Griffith University, Nathan, Brisbane, Queensland, AUSTRALIA.

    2Environmental Futures Research Institute, Griffith University, Nathan, Brisbane, Queensland, AUSTRALIA

    DOI: 10.5530/pc.2023.2.13

    ABSTRACT

    Introduction: Due to the development of bacterial strains that are resistant to multiple antibiotics, the development of new antibiotic therapies has become a priority for medical research. Traditional plant medicines are important leads for the discovery of new therapies and the search for novel antibiotic plant-based treatments has received substantial recent attention. The family Fabaceae is widely used therapeutically in many areas of the world, including for the treatment of bacterial diseases. Despite this, many members of this family are yet to be examined extensively for therapeutic properties. The endemic Australian species Jacksonia scoparia R.Br. was screened for antibacterial activity in this study against a panel of bacterial pathogens. Materials and Methods: The growth inhibitory activity of J. scoparia leaf extracts against a panel of bacterial pathogens was investigated by disc diffusion assay. Toxicity was examined using the Artemia franciscana lethality assay (ALA). Results: The methanolic and aqueous J. scoparia leaf extracts were devoid of inhibitory activity against panels of gram-positive and gram-negative bacteria. The extracts were non-toxic following 24 hr exposure in the ALA assay. Conclusion: The J. scoparia leaf extracts lacked bacterial growth inhibitory activity. However, these extracts may have other therapeutic properties and testing against protozoa, fungi, virus and tumour cells is required.

    Keywords: Fabaceae, Dogwood, Antibiotic resistance, Australian plant, Traditional medicine, Antibacterial activity, Medicinal plants, Toxicity.

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    About Journal
    About Journal

    Pharmacognosy Communications [Phcog Commn.] is a quarterly journal published by Phcog.Net. It is a peer reviewed journal aiming to publish high quality original research articles, methods, techniques and evaluation reports, critical reviews, short communications, commentaries and editorials of all aspects of medicinal plant research. The journal is aimed at a broad readership, publishing articles on all aspects of pharmacognosy, and related fields. The journal aims to increase understanding of pharmacognosy as well as to direct and foster further research through the dissemination of scientific information by the publication of manuscripts. The submission of original contributions in all areas of pharmacognosy are welcome.
    Indexed and Abstracted in : Chemical Abstracts, Excerpta Medica / EMBASE, Google Scholar, CABI Full Text, Ulrich’s International Periodical Directory, ProQuest, Journalseek & Genamics, PhcogBase, EBSCOHost, Academic Search Complete, Open J-Gate, SciACCESS.
    Rapid publication: Average time from submission to first decision is 30 days and from acceptance to In Press online publication is 45 days.
    Open Access Journal: Phcog Commn. is an open access journal, which allows authors to fund their article to be open access from publication.

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