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    Pharmacognosy Communications
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    Pharmacognosy Communications
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    Review Article

    Potential Use of Helicteres isora L. in Diabetes Mellitus: A Systematic Review of Scientific Literature

    Web AdminBy Web AdminNovember 10, 2023Updated:November 10, 2023No Comments2 Mins Read
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    Kamatchi Sundara Saravanan*, Radhakrishnan Gowri, Karthik Kumar Ramesh, Sanjana Shetty, Soubhagya Maity

    Department of Pharmacognosy, Faculty of Pharmacy, M S Ramaiah University of Applied Sciences, Bangalore, Karnataka, INDIA.

    DOI: 10.5530/pc.2023.4.26

    ABSTRACT

    Introduction: Plant-based medicines have been in use over the years for the management and treatment of various ailments including diabetes. The current study was undertaken to explore and compile the research evidence on Helicteres isora L. (Sterculiaceae) in the management of diabetes. Materials and Methods: Peer-reviewed literature was retrieved during January 2023 from databases comprising of PubMed, Science Direct, Springer and LILACS. The obtained literature was initially subjected to title and abstract screening, followed by full-text screening. Results: The study includes 12 articles that were chosen among a total of 111 articles retrieved through various sources. The selected articles reported either in vitro assay or in vivo evaluation of various extracts of H. isora bark, fruit, or root for its anti-diabetic property. The duration of the in vivo evaluation studies were up to 30 days in Wistar rat/Swiss albino mice/C57BL mice. The diabetogenic agents used were either Streptozotocin (STZ) or alloxan, while the reference drugs used comprised of tolbutamide, pioglitazone, glibenclamide, insulin, or metformin. A significant anti-diabetic property of various parts of H. isora were reported in the reviewed studies. Conclusion: The available evidence demonstrates the potential of H. isora against diabetes as it holds significant glucose-lowering effects in the reported screened models. Bioactivity-guided fractionation followed by elucidation of the mechanism of action will be useful in establishing the application of the plant species in diabetes.

    Keywords: Helicteres isora, Diabetes, Root, Bark, Fruit.

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    About Journal
    About Journal

    Pharmacognosy Communications [Phcog Commn.] is a quarterly journal published by Phcog.Net. It is a peer reviewed journal aiming to publish high quality original research articles, methods, techniques and evaluation reports, critical reviews, short communications, commentaries and editorials of all aspects of medicinal plant research. The journal is aimed at a broad readership, publishing articles on all aspects of pharmacognosy, and related fields. The journal aims to increase understanding of pharmacognosy as well as to direct and foster further research through the dissemination of scientific information by the publication of manuscripts. The submission of original contributions in all areas of pharmacognosy are welcome.
    Indexed and Abstracted in : Chemical Abstracts, Excerpta Medica / EMBASE, Google Scholar, CABI Full Text, Ulrich’s International Periodical Directory, ProQuest, Journalseek & Genamics, PhcogBase, EBSCOHost, Academic Search Complete, Open J-Gate, SciACCESS.
    Rapid publication: Average time from submission to first decision is 30 days and from acceptance to In Press online publication is 45 days.
    Open Access Journal: Phcog Commn. is an open access journal, which allows authors to fund their article to be open access from publication.

    © 2025 Pharmacognosy Communications. Maintained by Manuscript TechnoMedia LLP.

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