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    Pharmacognosy Communications
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    Pharmacognosy Communications
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    Research Article

    Effect of Basella rubra L. leaf extract on haematological parameters and amylase activity

    wadmin1By wadmin1July 1, 2012Updated:August 7, 2021No Comments2 Mins Read
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    Deep Shikha Sonkar,1* Rajiv Gupta,1 Shubhini A. Saraf1
    1Faculty of Pharmacy, Babu Banarasi Das National Institute of Technology & Management, Dr. Akhilesh Das Nagar, Lucknow – 227105 (U.P.), India

    Pharmacognosy Communications,2012,2,3,10-13
    DOI: 10.5530/pc.2012.3.3
    Published:July 2012
    Type: Research Article

    ABSTRACT

    Introduction: Basella rubra is a plant species commonly known as Poi (family Basellacea) found in almost every part of India, except hills. Poi possesses several folkloric uses, having beneficial effects in haemorrhagic diseases and as a tonic. In the present study, the effects of ethanolic and aqueous extract of Basella rubra (Poi) leaves were investigated for haematological parameters on normal Swiss mice and amylase activity on Wistar rats. Methods: Ethanolic and aqueous extracts of the plant (dosed at 100 and 200 mg/kg body weight) were administered to mice in different test groups for a period of 14 days for determination of haematological parameters. Aqueous, ethanolic and hexane extracts were given (200 mg/kg body weight) to the test group animals (Wistar rats) for the determination of amylase activity. The control group received distilled water for a period of 7 days. Result: There was an increase in the haematological parameters (RBC, WBC, Hb and PCV. The plant extracts caused a significant increase in the total bilirubin content. The aqueous and ethanolic extracts of 200 mg/kg showed significant increase (P < 0.05) in total bilirubin content but no significant increase was observed in aqueous and ethanolic extract (100 mg/kg) treated mice. There was also an increase in the amylase content in the hexane and ethanolic group animals and a decrease of amylase content in aqueous extract containing animals as compared to control group. Conclusion: It can be concluded that the commom plant B. rubra leaf has beneficial haematological properties in Swiss mice. In addition, the extract can prevent various complications of diabetes. ‘

    Key words: Basella rubra, Poi, haematological parameters, amylase activity

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    About Journal

    Pharmacognosy Communications [Phcog Commn.] is a quarterly journal published by Phcog.Net. It is a peer reviewed journal aiming to publish high quality original research articles, methods, techniques and evaluation reports, critical reviews, short communications, commentaries and editorials of all aspects of medicinal plant research. The journal is aimed at a broad readership, publishing articles on all aspects of pharmacognosy, and related fields. The journal aims to increase understanding of pharmacognosy as well as to direct and foster further research through the dissemination of scientific information by the publication of manuscripts. The submission of original contributions in all areas of pharmacognosy are welcome.
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