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    Pharmacognosy Communications
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    Pharmacognosy Communications
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    Research Article

    A Comparative Study on the Anti-Diabetic Potential of Aloe vera Gel and Fenugreek Seeds on Experimentally induced Diabetic Rats

    wadmin1By wadmin1January 1, 2012Updated:August 6, 2021No Comments1 Min Read
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    M. Vanitha1, T.Karpagam 2*, B.Varalakshmi 2, R. Suja Pandian1

    1PG and Research Department of Biochemistry, PRIST University, Thanjavur -614904, Tamil Nadu. India.

    2Department of Biochemistry, Shrimati Indira Gandhi College, Tiruchirappalli-620002, Tamilnadu, India.

    Pharmacognosy Communications,2012,2,1,57-61
    DOI: 10.5530/pc.2012.1.10
    Published:january 2012
    Type: Research Article

    ABSTRACT

    In the present study, the anti-diabetic property of an ethanolic extract of Aloe vera leaf gel and fine crude powder of Fenugreek seeds were compared. Oral administration of Aloe vera gel extract at a concentration of 300 mg/kg body weight and Fenugreek seeds powder extract at a concentration of 2g/kg body weight to alloxan-induced diabetes in rats significantly decreased the levels of blood glucose and glycosylated hemoglobin. The increased levels of lipid peroxidation in the pancreas of diabetic rats were reverted back to near normal levels after the treatment with Aloe vera gel and Fenugreek seeds powder extract. A significant increase was observed in SOD, vitamin C, vitamin E levels in Aloe vera gel and Fenugreek seeds powder extract treated rats. These extracts were also more effective than glibenclamide in restoring the levels to near normal.

    Key Words:Aloe vera, Fenugreek seeds, Alloxan-induced diabetes, anti-diabetic.

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    About Journal
    About Journal

    Pharmacognosy Communications [Phcog Commn.] is a quarterly journal published by Phcog.Net. It is a peer reviewed journal aiming to publish high quality original research articles, methods, techniques and evaluation reports, critical reviews, short communications, commentaries and editorials of all aspects of medicinal plant research. The journal is aimed at a broad readership, publishing articles on all aspects of pharmacognosy, and related fields. The journal aims to increase understanding of pharmacognosy as well as to direct and foster further research through the dissemination of scientific information by the publication of manuscripts. The submission of original contributions in all areas of pharmacognosy are welcome.
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