Facebook Twitter Instagram
    • Home
    • About Journal
      • Aim and Scope
      • Editorial Board
      • Indexing Info
      • Contact Us
    • Browse Issues
      • Articles in Press
      • Current Issue
      • Past Issues
    • For Authors
      • Instructions to Authors
      • Article Processing Charges
      • Submit your article
      • Downloads
    Facebook Twitter Instagram
    Pharmacognosy Communications
    • Home
    • About Journal
      • Aim and Scope
      • Editorial Board
      • Indexing Info
      • Contact Us
    • Browse Issues
      • Articles in Press
      • Current Issue
      • Past Issues
    • For Authors
      • Instructions to Authors
      • Article Processing Charges
      • Submit your article
      • Downloads
    Pharmacognosy Communications
    retyeyutreu
    Research Article

    Formulation and evaluation of oil entrapped floating beads of Piperine for peptic ulcers

    wadmin1By wadmin1January 1, 2012Updated:August 6, 2021No Comments2 Mins Read
    Facebook Twitter Pinterest LinkedIn Tumblr WhatsApp Email
    Share
    Facebook Twitter LinkedIn WhatsApp Pinterest Email

    B. Bindu Madhavi1, R. Ramalingam1, A. Ravinder Nath1 and David Banji2.

    1Department of Pharmacy, Osmania University, Hyderabad, India. 500017.

    2Department of Pharmacology, Nalanda College of Pharmacy, Nalgonda. India. 508001.

    Pharmacognosy Communications,2012,2,37-41
    DOI: 10.5530/pc.2012.1.7
    Published:january 2012
    Type: Research Article

    ABSTRACT

    Background: Peptic ulcers remain a challenge for identifying more effective and safer anti-ulcer therapies. Over the last few decades herbs have become the major source for the treatment of various diseases. The common spice piperine has shown a significant role in healing peptic ulcers. A fatty diet including olive oil has also proved effective for its anti ulcer activity. Objective: A formulation of floating piperine beads with the olive oil entrapment, to reside in the gastric environment, was tested for its therapeutic value. Materials and Methods: Floating beads wereprepared by the ionic gellation method, followed by air drying. Results: The prepared beads showed entrapment efficiency in the range of 75-85% with flotation for more than 12 hours. The inclusion of HPMC prolonged the drug release up to 12 hours. Conclusion: From the results it can be concluded that piperine in the form of olive oil entrapped floating beads is beneficial in treating peptic ulcers because of its longer residence time at the site of action and also because of the additive anti-secretary activity of the oil.

    Key Words:Anti ulcer activity, floating beads, Hydroxy Propyl Methyl Cellulose, olive oil, piperine.

    Download PDF
    Share. Facebook Twitter Pinterest LinkedIn Tumblr WhatsApp Email
    About Journal
    About Journal

    Pharmacognosy Communications [Phcog Commn.] is a quarterly journal published by Phcog.Net. It is a peer reviewed journal aiming to publish high quality original research articles, methods, techniques and evaluation reports, critical reviews, short communications, commentaries and editorials of all aspects of medicinal plant research. The journal is aimed at a broad readership, publishing articles on all aspects of pharmacognosy, and related fields. The journal aims to increase understanding of pharmacognosy as well as to direct and foster further research through the dissemination of scientific information by the publication of manuscripts. The submission of original contributions in all areas of pharmacognosy are welcome.
    Indexed and Abstracted in : Chemical Abstracts, Excerpta Medica / EMBASE, Google Scholar, CABI Full Text, Ulrich’s International Periodical Directory, ProQuest, Journalseek & Genamics, PhcogBase, EBSCOHost, Academic Search Complete, Open J-Gate, SciACCESS.
    Rapid publication: Average time from submission to first decision is 30 days and from acceptance to In Press online publication is 45 days.
    Open Access Journal: Phcog Commn. is an open access journal, which allows authors to fund their article to be open access from publication.

    © 2025 Pharmacognosy Communications. Maintained by Manuscript TechnoMedia LLP.

    Type above and press Enter to search. Press Esc to cancel.

    Scroll Up