Facebook Twitter Instagram
    • Home
    • About Journal
      • Aim and Scope
      • Editorial Board
      • Indexing Info
      • Contact Us
    • Browse Issues
      • Articles in Press
      • Current Issue
      • Past Issues
    • For Authors
      • Instructions to Authors
      • Article Processing Charges
      • Submit your article
      • Downloads
    Facebook Twitter Instagram
    Pharmacognosy Communications
    • Home
    • About Journal
      • Aim and Scope
      • Editorial Board
      • Indexing Info
      • Contact Us
    • Browse Issues
      • Articles in Press
      • Current Issue
      • Past Issues
    • For Authors
      • Instructions to Authors
      • Article Processing Charges
      • Submit your article
      • Downloads
    Pharmacognosy Communications
    retyeyutreu
    Research Article

    Isolation of Phytoconstituents and Evaluation of Anti-inflammatory Activity of the Leaves of Abelmoschus manihot

    wadmin1By wadmin1October 1, 2011Updated:August 7, 2021No Comments2 Mins Read
    Facebook Twitter Pinterest LinkedIn Tumblr WhatsApp Email
    Share
    Facebook Twitter LinkedIn WhatsApp Pinterest Email

    P.S. Jain, A.A. Todarwal, S.B. Bari, S.J. Surana.
    Department of Pharmaceutical Chemistry, R. C. Patel Institute of Pharmaceutical Education and Research, Shirpur, Dist: Dhule (M.S.) India 425 405

    Pharmacognosy Communications,2011,1,2,2-7
    DOI:10.5530/pc.2011.2.2
    Published: Oct 2011
    Type: Research Article

     

    ABSTRACT

    The present study was carried out to isolate the phytoconstituents and evaluate the anti-inflammatory activity of the petroleum ether and methanol extract of Abelmoschus manihot (Malvaceae) leaves using paw edema model. The air-dried, powdered laeves (1 Kg) were extracted over Soxhlet with petroleum ether and methanol. Two steryl alcohol, named 1-dodecanol (1) and 1-tridecanol (2) from petroleum ether exctract, together with a known acid ester, 1-tridecanoic acid methyl ester (3) from methanol extract, were isolated from Abelmoschus manihot. Their structures were elucidated by spectroscopic methods. The crude dried petroleum ether (10 g) and methanol (25 g) extracts was prepared at doses of 100, 200 and 400 mg/kg, and evaluated for anti-inflammatory using the carrageenan and histamine-induced paw edema test. The results obtained indicate that the extracts possessed significant (p < 0.01) anti-inflammatory activity, which was found to be dose-dependent. This study showed that the petroleum ether and methanol extracts of Abelmoschus manihot woody stems possess potential pharmacological active constituents responsible for inhibition of the inflammation effect.

    Key words: Abelmoschus manihot, Steryl alcohol, Acid methyl ester, Anti-inflammatory activity.

    Download PDF
    Share. Facebook Twitter Pinterest LinkedIn Tumblr WhatsApp Email
    About Journal
    About Journal

    Pharmacognosy Communications [Phcog Commn.] is a quarterly journal published by Phcog.Net. It is a peer reviewed journal aiming to publish high quality original research articles, methods, techniques and evaluation reports, critical reviews, short communications, commentaries and editorials of all aspects of medicinal plant research. The journal is aimed at a broad readership, publishing articles on all aspects of pharmacognosy, and related fields. The journal aims to increase understanding of pharmacognosy as well as to direct and foster further research through the dissemination of scientific information by the publication of manuscripts. The submission of original contributions in all areas of pharmacognosy are welcome.
    Indexed and Abstracted in : Chemical Abstracts, Excerpta Medica / EMBASE, Google Scholar, CABI Full Text, Ulrich’s International Periodical Directory, ProQuest, Journalseek & Genamics, PhcogBase, EBSCOHost, Academic Search Complete, Open J-Gate, SciACCESS.
    Rapid publication: Average time from submission to first decision is 30 days and from acceptance to In Press online publication is 45 days.
    Open Access Journal: Phcog Commn. is an open access journal, which allows authors to fund their article to be open access from publication.

    © 2025 Pharmacognosy Communications. Maintained by Manuscript TechnoMedia LLP.

    Type above and press Enter to search. Press Esc to cancel.

    Scroll Up