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    Pharmacognosy Communications
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    Pharmacognosy Communications
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    Research Article

    Cassane-type diterpenoids from the genus Caesalpinia

    wadmin1By wadmin1July 1, 2011Updated:August 5, 2021No Comments1 Min Read
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    R. A. Dickson1, T. C. Fleischer1, P. J. Houghton2

    1Department of Pharmacognosy, Faculty of Pharmacy and Pharmaceutical, KNUST Kumasi, Ghana.

    2Pharmacognosy Research Laboratories, Pharmaceutical Sciences Research Division, King’s College London, Franklin-Wilkins Building, 150 Stamford Street, London SE1 9NH, UK

    Pharmacognosy Communications,2011,1,1,63-77
    DOI:10.5530/pc.2011.1.4
    Published: July 2011
    Type: Research Article

    ABSTRACT

    Medicinal plants belonging to the Caesalpinia (Ceasalpiniaceae) genus are widely distributed in most tropical countries and have been frequently employed in folkloric medicine worldwide in the treatment of various ailments including skin diseases, malaria, cancer, infections, erectile dysfunction, pain and wounds. Interest in this genus has increased considerably over the years and the biological properties of different phytoconstituents, such as the cassane-type diterpenoid isolates, have been studied. Over the past 60 years, a number of cassane-type diterpenoids have been isolated from species of this genus and some of them possess interesting biological activities. Recently, three novel cassane-type diterpenoids, benthaminin 1, 2 and 3, which demonstrate antimicrobial and antioxidant properties, have been isolated from Caesalpinia benthamiana growing in Ghana. This review seeks among other things to collate all these isolated compounds, recognising their diversity and commenting on their relevance as bioactive compounds.

    Key words: Cassane-type diterpenoids, Caesalpinia, Ceasalpiniaceae, Biological activity.

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    About Journal
    About Journal

    Pharmacognosy Communications [Phcog Commn.] is a quarterly journal published by Phcog.Net. It is a peer reviewed journal aiming to publish high quality original research articles, methods, techniques and evaluation reports, critical reviews, short communications, commentaries and editorials of all aspects of medicinal plant research. The journal is aimed at a broad readership, publishing articles on all aspects of pharmacognosy, and related fields. The journal aims to increase understanding of pharmacognosy as well as to direct and foster further research through the dissemination of scientific information by the publication of manuscripts. The submission of original contributions in all areas of pharmacognosy are welcome.
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