Peter Muchoki Githinji1, Jeremiah Waweru Gathirwa2,*, Margret Mwihaki Ng’ang’a1, Alex King’ori Machocho1 1Department of Chemistry, Kenyatta University, Nairobi, KENYA. 2Kenya Medical Research Institute, Centre for Traditional Medicine and Drug Research, Nairobi, KENYA. Pharmacognosy Communications,2020,10,3,130-133.DOI:10.5530/pc.2020.3.25Published: July 2020Type: Original Article ABSTRACT Introduction: Plants of the genus Grewia have been used as medicinal agents to treat several diseases. Grewia species are reported in use as folk medicine for the treatment of malaria, diarrhoea, dysentery, typhoid fever, small pox, cough, irritable condition of intestine and bladder among others. Methods: The stem back material of Grewia plagiophylla was extracted using CH2Cl2: MeOH (1:1). Fractionation and Isolation of the extract was done using column…
Author: wadmin1
Sambhav Jain, Aditya Ganeshpurkar*, Nazneen Dubey Shri Ram Institute of Technology-Pharmacy, Jabalpur, Madhya Pradesh, INDIA. Pharmacognosy Communications,2020,10,3,134-135.DOI:10.5530/pc.2020.3.26Published: July 2020Type: Research Article ABSTRACT Introduction: Azadirachta indica is commonly known as Neem, is found abundantly in India. This plant is used in the treatment of infections, pain and wounds. Methods: The aim of present study to investigate in silico molecular docking study used for three phytoconstituents β-sitosterol(22,23-Dihydrostigmasterol, Stigmast-5-en-3-ol, β -Sitosterin), isomeldenin and nimbandiol from Azadirachtaindica to identify whether these compounds interact with the COX-2 and NOs. The structure of neem constituents were downloaded from Pubchem and structure of enzymes/ proteins were obtained from protein data bank. Results: Among all the…
Muhammad Jawad Yousaf Zai1, Ian Edwin Cock1,2,* 1School of Environment and Science, Nathan Campus, Griffith University, 170 Kessels Rd, Nathan, Brisbane, Queensland, AUSTRALIA. 2Environmental Futures Research Institute, Griffith University, 170 Kessels Rd, Nathan, Brisbane, Queensland, AUSTRALIA. Pharmacognosy Communications,2020,10,3,136-139.DOI:10.5530/pc.2020.3.27Published: July 2020Type: Research Article ABSTRACT Introduction: Trachyspermum ammi leaves and seeds have been used as dietary supplements and to treat multiple pathogenic diseases in several traditional healing systems. Despite this, their therapeutic properties have been poorly studied. Methods: Chloroform, ethyl acetate, hexane, methanol and water extracts of T. ammi were prepared and tested and the activity was compared to that of standard antibiotics for their in vitro antibacterial activity against…
Ian Edwin Cock1,2,*1School of Environment and Science, Nathan Campus, Griffith University, 170 Kessels Rd, Nathan, Brisbane, Queensland, AUSTRALIA.2Environmental Futures Research Institute, Griffith University, 170 Kessels Rd, Nathan, Brisbane, Queensland, AUSTRALIA. Pharmacognosy Communications,2020,10,3,140-142.DOI:10.5530/pc.2020.3.28Published: July 2020Type: The Janus Corner ABSTRACT Since the onset of the current Covid-19 pandemic, the search has been on for methods to provide immunity, decrease mortality and lessen the symptoms of the disease. Much of the current research focuses is on the development of effective vaccines and with good reason. The discovery of an effective vaccine promises the establishment of widespread immunity to the SARS-COV-2 virus and is…
Ian Edwin Cock1,2,* 1Environmental Futures Research Institute, Griffith University, 170 Kessels Rd, Nathan, Brisbane, Queensland, AUSTRALIA. 2School of Environment and Science, Nathan Campus, Griffith University, 170 Kessels Rd, Nathan, Brisbane, Queensland-4111, AUSTRALIA. Pharmacognosy Communications,2020,10,3,143.DOI:10.5530/pc.2020.3.29Published: July 2020Type: Medicinal Plant Images ABSTRACT Petalostigma triloculorae (commonly known as quinine bush) unripe fruit and leaves. Petalostigma is an Australian Euphorbiaceae genus which consists of 7 species. They grow to between 2 and 10 metres in height and have bright orange fruit (when ripe). Petalostigma species were used extensively by indigenous Australians to treat a myriad of bacterial, fungal and viral diseases.1 P. pubescens bark and fruit decoctions…
Pharmacognosy Communications,2020,10,3,144.Published:July 2020Type:Upcoming Events Download PDF
Ian Edwin Cock1,2,*1Environmental Futures Research Institute, Nathan Campus, Griffith University, Nathan, Brisbane, Queensland, AUSTRALIA.2School of Natural Sciences, Nathan Campus, Griffith University, Kessels Rd, Nathan, Brisbane, Queensland, AUSTRALIA. Pharmacognosy Communications,2020,10,2,62.DOI:10.5530/pc.2020.2.12Published: April 2020Type: Editorial Dear Readers and Authors, I am pleased to bring you volume 9, issue 2 of Pharmacognosy Communications. In this issue we present new research reports examining the pharmacognosy of several important medicinal plants, including studies examining the antimicrobial activity of the Indian medicinal plants Shorea robusta Geartn f and Dipterocarpus turbinatus Gaertn f, the South American plant Tabebuia impetiginosa (Mart. Ex. DC. Mattos), the Australian species Alphitonia excela (Fenzl) Benth. Acronychia acidula F. Muell. and Pouteria australis (R.Br.) Baehni, as…
Shagun Dubey Upadhyay1,*, Yusra Ahmad2, Seema Kohli11Department of Pharmacy, Government Kalaniketan Polytechnic College Jabalpur, Madhya Pradesh, INDIA.2Faculty of Pharmacy, Uttarakhand Technical University, Dehradun, Uttarakhand, INDIA. Pharmacognosy Communications,2020,10,2,63-66.DOI:10.5530/pc.2020.2.13Published: April 2020Type: Review Article ABSTRACT Introduction: Galantamine a traditional herb has also been explored for a number of pharmacological effects. Today, galantamine has been observed for its nootropic effect. Methodology: The objective of this review is to study the evidence of effectiveness and pharmacological effects of galantamine. The preclinical and randomized controlled clinical trials pertaining to studies of galantamine are included. Chemical properties of galantamine and its structure activity relationship pertaining to various…
Ian Edwin Cock1,2,*1School of Natural Sciences, Griffith University, 170 Kessels Rd, Nathan, Brisbane, Queensland, AUSTRALIA.2Environmental Futures Research Institute, Griffith University, 170 Kessels Rd, Nathan, Brisbane, Queensland, AUSTRALIA. Pharmacognosy Communications,2020,10,2,67-74.DOI:10.5530/pc.2020.2.14Published: April 2020Type: Original Article ABSTRACT Introduction: Alphitonia excelsa (Fenzl) Benth. is a large tree that is native to the east coast and northern regions of Australia. Decoctions and infusions produced from the leaves were used by the first Australians to treat a variety of bacterial diseases. Despite this, A. excelsa leaf extractions have not been rigorously examined for antibacterial properties against many pathogens. Methods: The antimicrobial activity of A. excelsa leaf…
Alejandra Fernandez1,2, Ian Edwin Cock1,2,* 1School of Environment and Science, Griffith University, 170 Kessels Rd, Nathan, Brisbane, Queensland, AUSTRALIA. 2Environmental Futures Research Institute, Griffith University, 170 Kessels Rd, Nathan, Brisbane, Queensland, AUSTRALIA. Pharmacognosy Communications,2020,10,2,75-82.DOI:10.5530/pc.2020.2.15Published: April 2020Type: Original Article ABSTRACT Introduction: Tabebuia impetiginosa (Mart. Ex DC. Mattos) bark has been used to treat inflammation and cancer, as well as a variety of pathogenic diseases, in traditional South American healing systems. As practitioners of complementary medicine frequently use herbal medicines concurrently with conventional antibiotics, the effects of both therapies in combination needs to be evaluated. Methods: The growth inhibitory activity of T. impetiginosa bark extracts was assessed against…