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A Review on Pharmacological Potential of Galantamine

Shagun Dubey Upadhyay1,*, Yusra Ahmad2, Seema Kohli1
1Department of Pharmacy, Government Kalaniketan Polytechnic College Jabalpur, Madhya Pradesh, INDIA.
2Faculty of Pharmacy, Uttarakhand Technical University, Dehradun, Uttarakhand, INDIA.

Pharmacognosy Communications,2020,10,2,63-66.
DOI:10.5530/pc.2020.2.13
Published: April 2020
Type: Review Article

ABSTRACT

Introduction: Galantamine a traditional herb has also been explored for a number of pharmacological effects. Today, galantamine has been observed for its nootropic effect. Methodology: The objective of this review is to study the evidence of effectiveness and pharmacological effects of galantamine. The preclinical and randomized controlled clinical trials pertaining to studies of galantamine are included. Chemical properties of galantamine and its structure activity relationship pertaining to various biological activities has also been documented. Result and Conclusion: The review revealed protective effects of galantamine on functions and integrity of liver, brain and memory impairment. The various independent studies have demonstrated anti-alzheimer, antioxidant, antidiabetic and neuroprotective effect of galantamine. The present review highlights current information and health-promoting effects of a traditionally known drug galantamine.

Key words: Anti-alzheimer, Anti-diabetic, Nootropic, Neuroprotective, Galantamine.

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