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    Pharmacognosy Communications
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    Pharmacognosy Communications
    retyeyutreu
    Original Article

    Westringa fruticosa (Willd.) Druce Leaf and Flower Extracts Lack Antibacterial Activity and are Non-toxic in vitro

    wadmin1By wadmin1June 1, 2019Updated:August 10, 2021No Comments2 Mins Read
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    Getmore Chikowe1, Lindi Mpala1, Ian Edwin Cock1,2,*

    1School of Environment and Science, Nathan Campus, Griffith University, 170 Kessels Rd, Nathan, Brisbane, Queensland, AUSTRALIA.

    2Environmental Futures Research Institute, Griffith University, 170 Kessels Rd, Nathan, Brisbane, Queensland, AUSTRALIA.

    Pharmacognosy Communications,,2019,9,3,100-105.
    DOI:10.5530/pc.2019.3.21
    Published:June 2019
    Type:Original Article

    ABSTRACT

    Introduction: Closely related plant species often share similar secondary metabolites and bioactivities and are therefore good targets for bioactivity testing when one or more species within a family are known to possess therapeutic properties. The family Lamiaceae has a long history of medicinal usage globally. Many species are known to have therapeutic properties, several species of which have well established antibacterial bioactivities. Methods: The ability of Westringa fruticosa leaf and flower extracts to inhibit the growth of a panel of bacterial and fungal pathogens was investigated by disc diffusion assay. Toxicity was examined using the Artemia franciscana nauplii bioassay. Results: W. fruticosa leaf methanolic and aqueous extracts were both completely ineffective at inhibiting the growth of gram-positive and gram-negative panels of bacteria, as well as fungi. The extracts were non-toxic or of low toxicity in the Artemia bioassay following 24 h exposure. Conclusion: Despite the taxonomic relationship to several bioactive Laminaceae spp., W. fruticosa leaf and flower extracts were completely ineffective bacterial and fungal growth inhibitors. However, these extracts may have other therapeutic properties and testing against protozoa, virus and tumour cells is required. 

    Keywords:Antibacterial activity, Australian plant, Coastal rosemary, Lamiaceae, Medicinal plants, Toxicity, Traditional medicine
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    About Journal
    About Journal

    Pharmacognosy Communications [Phcog Commn.] is a quarterly journal published by Phcog.Net. It is a peer reviewed journal aiming to publish high quality original research articles, methods, techniques and evaluation reports, critical reviews, short communications, commentaries and editorials of all aspects of medicinal plant research. The journal is aimed at a broad readership, publishing articles on all aspects of pharmacognosy, and related fields. The journal aims to increase understanding of pharmacognosy as well as to direct and foster further research through the dissemination of scientific information by the publication of manuscripts. The submission of original contributions in all areas of pharmacognosy are welcome.
    Indexed and Abstracted in : Chemical Abstracts, Excerpta Medica / EMBASE, Google Scholar, CABI Full Text, Ulrich’s International Periodical Directory, ProQuest, Journalseek & Genamics, PhcogBase, EBSCOHost, Academic Search Complete, Open J-Gate, SciACCESS.
    Rapid publication: Average time from submission to first decision is 30 days and from acceptance to In Press online publication is 45 days.
    Open Access Journal: Phcog Commn. is an open access journal, which allows authors to fund their article to be open access from publication.

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