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    Pharmacognosy Communications
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    Pharmacognosy Communications
    retyeyutreu
    Original Article

    Cordyline rubra Otto and A. Dietr. Leaf and Fruit Extracts Lack Antibacterial Activity and are Non-toxic in vitro

    wadmin1By wadmin1September 1, 2019Updated:August 10, 2021No Comments2 Mins Read
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    Lindy Mpala1, Getmore Chikowe2, Ian Edwin Cock1,2,*

    1School of Environment and Science, Nathan Campus, Griffith University, Nathan, Brisbane, Queensland, AUSTRALIA.

    2Environmental Futures Research Institute, Griffith University, Nathan, Brisbane, Queensland, AUSTRALIA

    Pharmacognosy Communications,2019,9,4,130-134.
    DOI:10.5530/pc.2019.4.27
    Published:September 2019
    Type:Original Article

    ABSTRACT

    Introduction: The development of bacterial strains that are resistant to multiple antibiotics has made the development of new antibiotics a priority for medical research. Traditional plant medicines are important leads for the discovery of new medicines. The family Agavaceae is widely used therapeutically in many areas of the world. Despite this, many members of this family are yet to be examined extensively for therapeutic properties. The species Cordyline rubra Otto and A. Dietr. was screened for antibacterial activity in this study. Methods: The ability of C. rubra leaf and fruit extracts to inhibit the growth of a panel of bacterial pathogens was investigated by disc diffusion assay. Toxicity was examined using the Artemia franciscana nauplii bioassay. Results: Methanolic C. rubra leaf and fruit extracts were completely ineffective at inhibiting the growth of gram-positive and gramnegative panels of bacteria. The extracts were also non-toxic or of low toxicity following 24 h exposure. Conclusion: C. rubra leaf and fruit extracts were completely ineffective bacterial growth inhibitors. However, these extracts may have other therapeutic properties and testing against protozoa, fungi, virus and tumour cells is required.

    Keywords:Antibacterial activity, Antibiotic resistance, Asparagaceae, Australian plant, Medicinal plants, Palm lily, Toxicity, Traditional medicine
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    About Journal
    About Journal

    Pharmacognosy Communications [Phcog Commn.] is a quarterly journal published by Phcog.Net. It is a peer reviewed journal aiming to publish high quality original research articles, methods, techniques and evaluation reports, critical reviews, short communications, commentaries and editorials of all aspects of medicinal plant research. The journal is aimed at a broad readership, publishing articles on all aspects of pharmacognosy, and related fields. The journal aims to increase understanding of pharmacognosy as well as to direct and foster further research through the dissemination of scientific information by the publication of manuscripts. The submission of original contributions in all areas of pharmacognosy are welcome.
    Indexed and Abstracted in : Chemical Abstracts, Excerpta Medica / EMBASE, Google Scholar, CABI Full Text, Ulrich’s International Periodical Directory, ProQuest, Journalseek & Genamics, PhcogBase, EBSCOHost, Academic Search Complete, Open J-Gate, SciACCESS.
    Rapid publication: Average time from submission to first decision is 30 days and from acceptance to In Press online publication is 45 days.
    Open Access Journal: Phcog Commn. is an open access journal, which allows authors to fund their article to be open access from publication.

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