GC-MS Analysis and Assessment of Antioxidant and Anthelmintic Potential of the Ethanolic Root Extract of Borassus flabellifer Linn.

Introduction: The present study was to investigate the phytocomponents by using GC-MS analysis, in-vitro antioxidant activity and the anthelmintic property of ethanolic extract of Borassus flabellifer Linn (EEBFL) root. Methods: EEBFL was prepared from roots of B. flabellifer by cold maceration. EEBFL was used to analyse phytocomponents by GCMS and the in-vitro antioxidant activity was quantified using are low he ABTS method. Anthelmintic activity was studied on Pheritima posthuma. Results: The phytochemical investigation by GC-MS study identified 15 components in the extract of B. flabellifer. In antioxidant activity, the percentage scavenging range from 32.33% to 61.66% (IC₅₀ 160±2.5) and by standard drug (ascorbic acid) 48.33% to 70.66% (IC₅₀ 105±4.33) using the ABTS method. For anthelmintic activity, EEBFL showed paralysis time ranging from 107 min to 127 min and a death time ranging from 148 min to 177 min comparted to the standard drug Albendazole (paralysis time 94 min to 62 min and death time 124 min to 136 min on Pheritima posthuma). Conclusion: Ethanolic B. flabellifer Linn root extract is an effective agent in the management of antioxidant and anthelmintic activities due to presence of biologically active phytocomponents.