Error message

Deprecated function: The each() function is deprecated. This message will be suppressed on further calls in theme_biblio_custom() (line 367 of /home/phcogcommn/

Schisandra chinensis, Five Flavor Berry, a Traditional Chinese Medicine and a Super-Fruit from North Eastern China


Pharmacognosy Communications,2021,11,1,13-21.
Published:January 2021
Type:Review Article

Schisandra chinensis, Five Flavor Berry, a Traditional Chinese Medicine and a Super-Fruit from North Eastern China

Wenli Sun1,2, Mohamad Hesam Shahrajabian1,2, Qi Cheng1,2,*

1Biotechnology Research Institute, Chinese Academy of Agricultural Sciences, Beijing, CHINA.

2Nitrogen Fixation Laboratory, Qi Institute, Building Chuangye Road, Jiaxing, Zhejiang, CHINA.


Introduction: The aim of this review was to summarize the most important traditional and modern health benefits of Schisanda berry. Methods: We used PubMed, Science Direct and Google to search for and collect scientific publication for a full evaluation of current evidence in the literature indicating the potential role of Schisanda berry. Results: The traditional Chinese medicine (TCMs) is essential components of alternative medicines. Schisandra berry (Schisandra chinensis (Turcz.) Baill. (Magnoliaceae) or Wu-Wei-Zi, which means the fruit of five tastes is a commonly used herb in traditional Chinese medicine (TCM). The five tastes of Schisandra berry refer to its influence on the five visceral organs in the body. It is one of the oldest medicinal plants used in East of Asia, especially traditional Chinese medicine. S. chinensis is mainly distributed in provinces in northern China including Heilongjiang, Jilin and Liaoning. S. chinensis can treat lung-Qi and kidney-Yin deficiencies, relieve coughs and asthma and stop persistent diarrhea. S. chinensis has been used to treat sleep disorder in traditional Chinese medicine and a tonic for kidney and brain in traditional Chinese medicine. Its extracts may apply as a preservative and as an additive to increase the flavor, taste and nutritional value of food. The five important components of S. chinensis are Schisandrol B, Schisandrin A, γ-Schisandrin, Gomisin N and Schisandrin C. Conclusion: The most important pharmacological effects of Schisandrol B are antiallergy, liver protection and anticarcinogenic effects; Schisandrin A has role in liver protection and anti-carcinogenic effect; γ-Schisandrin has liver protection and anti-carcinogenic effect, Gomisin N has anti-proliferative, pro-apoptis HepG2 cells, anti-hepatitis, anti-HIV, anti-carcinogenic effect; and Schisandrin C has protect liver, anti-HIV, anti-catchinogenic effect and anti-hepatitis. The treatment with natural herbal medicine which are also super-fruit and non-synthetic drug is recommended.

Founded:  In 2004, as the PHCOG.NET – a non-profit private organization dedicated to Natural Products Research leading to develop promising drugs. Our main mission is to make information on herbal drug research readily available in different formats to suit the individual needs.

Pharmacognosy Communications [Phcog Commn.] is a new quarterly journal published by Phcog.Net. It is a peer reviewed journal aiming to publish high quality original research articles, methods, techniques and evaluation reports, critical reviews, short communications, commentaries and editorials of all aspects of medicinal plant research. The journal is aimed at a broad readership, publishing articles on all aspects of pharmacognosy, and related fields. The journal aims to increase understanding of pharmacognosy as well as to direct and foster further research through the dissemination of scientific information by the  publication of manuscripts. The submission of original contributions in all areas of pharmacognosy are welcome.

The journal aims to cater the latest outstanding developments in the field of pharmacognosy and natural products and drug design covering but not limited to the following topics:

  • Pharmacognosy and pharmacognistic investigations
  • Research based ethnopharmacological evaluations
  • Biological evaluation of crude extracts, essential oils and pure isolates
  • Natural product discovery and evaluation
  • Mechanistic studies
  • Method and technique development and evaluation
  • Isolation, identification and structural elucidation of natural products
  • Synthesis and transformation studies

Distinctions:  The most widely read, cited, and known Pharmacognosy Communications and website is well browsed with all the articles published. More than 20,000 readers in nearly every country in the world each month

Aim and Scope | Editorial Board | Indexed & Abstracted | Instruction to Authors | Manuscript Submission & Charges

Subjects Covered : Natural Products, Pharmacognosy, Phytochemistry, Marine Pharmacognosy and Zoo Pharmacognosy
ISSN :2249-0159 (Print) ; 2249-0167 (Online) Frequency : Quarterly Rapid at a time publication (4 issues/year)

Indexed and Abstracted in : Chemical Abstracts, Excerpta Medica / EMBASE, Google Scholar, CABI Full Text, Ulrich’s International Periodical Directory, ProQuest, Journalseek & Genamics, PhcogBase, EBSCOHost, Academic Search Complete, Open J-Gate, SciACCESS.
Rapid publication: Average time from submission to first decision is 30 days and from acceptance to In Press online  publication is 45 days.
Open Access Journal: Phcog Commn. is an open access journal, which allows authors to fund their article to be open access from publication.