Alysha Bromley1, Ian E Cock1,2,* 1School of Environment and Science, Griffith University, Nathan, Queensland, AUSTRALIA. 2Centre for Planetary Health and Food Security, Nathan Campus, Griffith University, Nathan, Queensland, AUSTRALIA.DOI: 10.5530/pc.2022.1.4 ABSTRACT Background: Recent increases in the numbers of antibiotic resistant bacteria and corresponding decreases in antimicrobial discovery have focussed drug discovery efforts towards plant based medicines. Harpagophytum procumbens has been used in southern African traditional medicine for a variety of conditions including inflammation, and to treat bacterial infections. Despite this, investigations of the antibacterial activity of H. procumbens root extracts have been relatively neglected. Materials and Methods: The antimicrobial activity…
Author: Web Admin
Getmore Rumbudzai Chikowe1, Lindiwe Nomathemba Mpala1, I E Cock1,2,* 1Environmental Futures Research Institute, Griffith University, Brisbane, Queensland, AUSTRALIA. 2School of Environment and Science, Nathan Campus, Griffith University, Brisbane, Queensland, AUSTRALIA.DOI: 10.5530/pc.2022.1.5 ABSTRACT Introduction: The development of bacterial strains that are resistant to multiple antibiotics has made the discovery of new antibiotics a priority for medical research. Examination of plants for new antimicrobial agents is an attractive prospect and numerous recent studies have screened plants for antibacterial activity. Despite this, many plant species are yet to be tested for antibacterial activity. Lomandra hystrix Labill. is a perennial rhizomatus herb of the…
Ian Cock1,2,* 1School of Environment and Science, Griffith University, Brisbane, AUSTRALIA. 2Centre for Planetary Health and Food Security, Griffith University, Brisbane, AUSTRALIA.DOI: 10.5530/pc.2022.1.6 ABSTRACT Background: Engagement of students in the biosciences is essential to ensure a continued flow of quality medical, pharmaceutical and pharmacognosy researchers into the future. Methods: A suite of teaching modalities and philosophies were implemented into a first year university course aimed at engaging student interest in contemporary issues and current research in the biosciences and trialled over a period of 4 years. The curriculum was developed and adapted by incorporating strategies which resulted in positive outcomes…
I E Cock1,2,* 1School of Environment and Science, Nathan Campus, Griffith University, Nathan, Brisbane, Queensland, AUSTRALIA. 2Centre for Planetary Health and Food Security, Nathan Campus, Griffith University, Nathan, Brisbane, Queensland, AUSTRALIA.DOI: 10.5530/pc.2022.1.7 ABSTRACT A recent study from a Pohang University, Korea group has reported that the hydroflavone gossypeptin, which is found in relative abundance in Hibiscus sabdariffa L., has therapeutic effects in a 5XFAD Alzheimer’s Disease (AD) mouse model.1 That mouse strain possesses human APP and PSEN1 transgenes, which are linked to familial AD and are known to enhance β-amyloid protein accumulation in brain cells. Mice treated with gossypeptin displayed…
I E Cock1,2,* 1Environmental Futures Research Institute, Nathan Campus, Griffith University, Nathan, Brisbane, Queensland, AUSTRALIA. 2School of Natural Sciences, Nathan Campus, Griffith University, Nathan, Brisbane, Queensland, AUSTRALIA. DOI: 10.5530/pc.2022.1.8 Figure 1: Tasmannia lanceolata (Poir) A.C.Sm. (Family Winteraceae), commonly known as Tasmanian pepper or mountain pepper berry, is shrub which is endemic to the woodlands and cool temperate rainforests of Tasmania and the south-eastern region of the Australian mainland. The leaves, berries and bark of this plant have traditional uses as a food flavouring, and as a medicinal plant. Australian Aborigines used T. lanceolata as a therapeutic agent to treat stomach…
Disclaimer: The following conference dates and details have been provided using currently available information. Due to the rapidly changing nature of the current COVID-19 pandemic and the changes that may become necessary to due to local regulations and/or to ensure safety, these conferences may change prior to their commencement date. All reasonable attempts have been made to check and ensure the validity of these details. However, potential delegates are recommended to check these details with the conference organisers closer to the commencement date. Furthermore, as different regions and countries have different travel restrictions and requirements, it is strongly recommended that…
Franklyn Okechukwu Ohiagu1, Paul Chidoka Chikezie1,*, Chinwendu Maureen Chikezie2 1Department of Biochemistry, Imo State University, Owerri, NIGERIA. 2Department of Biochemistry, Federal University of Technology, Owerri, NIGERIA. Pharmacognosy Communications,2021,11,2,67-77.DOI:10.5530/pc.2021.2.15Published:April 2021Type:Review Article ABSTRACT Aim/Background: The evaluation of toxicological significance of medicinal plants is necessary prior to their use for drug development or for the purpose of improving the therapeutic efficacy of existing therapies. Regrettably, there is little information on the toxicity profiles of the chemical constituents of commonly used medicinal plants. Meanwhile, available information on the toxicity concerns of the use of medicinal plants are often taken for granted and ignored. Materials and Methods: The…
Shivani Lodha1,*, Shagun Upadhyay2 1Faculty of Pharmacy, Uttarakhand Technical University, Dehradun Uttarakhand, INDIA. 2Kalaniketan Polytechnic College, Jabalpur, Madhya Pradesh, INDIA. Pharmacognosy Communications,2021,11,2,78-80.DOI:10.5530/pc.2021.2.16Published:April 2021Type:Review Article ABSTRACT Herbal supplements are used widely all over the world for prevention, delaying onset, decreasing overall severity, and potential reversal of mental illness. The main aimof the overview is to communicate the latest observations regarding the effectiveness of herbal and nutraceutical supplements in the prevention, treatment, and delaying onset of symptomology related to schizophrenia and other schizoaffective disorders, also to explore their laentrole in the future of psychiatry and related health practices. The supplements and their…
Célia Barillot1,2, Ian Edwin Cock1,3,* 1Environmental Futures Research Institute, Griffith University, Brisbane, AUSTRALIA. 2School of Biology, Ecole de Biologie Industrielle (EBI), Cergy, FRANCE. 3School of Environment and Science, Griffith University, Brisbane, AUSTRALIA. Pharmacognosy Communications,2021,11,2,81-87.DOI:10.5530/pc.2021.2.17Published:April 2021Type:Original Article ABSTRACT Introduction: Kunzea ambigua (Sm.) Druce and Kunzea flavescens C.T. White and W.D. Francis are endemic Australian plants. Decoctions, infusions and essential oils produced from the leaves were used traditionally to treat a variety of bacterial diseases. Despite this, these species have not been rigorously examined for antibacterial properties against many pathogens. Methods: The antimicrobial activity of K. ambigua and K. flavescens essential oils and a K. ambigua hydrosol was investigated by disc diffusion and liquid…
Temilola Aina1, Victor Akpe2,3, Olubunmi Magbagbeola1, Ian Edwin Cock2,3,* 1Department of Biochemistry, College of Medicine (Idi-Araba), University of Lagos, NIGERIA. 2Environmental Futures Research Institute, Griffith University, Nathan Campus, QLD, AUSTRALIA. 3School of Environment and Science, Griffith University, Nathan Campus, QLD, AUSTRALIA. Pharmacognosy Communications,2021,11,2,88-94.DOI:10.5530/pc.2021.2.18Published:April 2021Type:Original Article ABSTRACT Background: Impairment of the normal progression of the cell cycle affects the growth and development of the daughter cells, which may result in cancer cell proliferation. Herein, we investigate the effect of flavonoid fractions of Hibiscus sabdariffa L. calyx on cell cycle progression in cervical cancer cells. Methods: Flavonoids (bound and free), lipids and aqueous fractions were extracted from…