Patil Avinash, Koli Swapneel, Patil Darshana and Phatak AnitaDepartment of Botany (Herbal Sciences), Birla College, Kalyan 421304, India (M.S.) Pharmacognosy Communications,2012,2,2,13-17DOI: 10.5530/pc.2012.2.3Published:April 2012Type: Reveiw Article ABSTRACT The use of plants as medicine is as old as human civilization. People of all ages in both developing and developed countries use plants in an attempt to cure various diseases and to get relief from physical sufferings. Natural products are a source for bioactive compounds and have potential for developing some novel therapeutic agents. Averrhoa carambola L., which is popularly known as the “Star Fruit” or “Kamrakh”, has various medicinal uses viz. antipruritic, antipyretic, anthelmintic,…
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Sunil Kumar, Vipin Kumar, Monika Rana and Dinesh KumarInstitute of Pharmaceutical Sciences, Kurukshetra University, Kurukshetra, Haryana, India Pharmacognosy Communications,2012,2,2,18-33DOI: 10.5530/pc.2012.2.4Published:April 2012Type: Reveiw Article ABSTRACT Diabetes is one of the major medical complications the world faces today. It is a common metabolic disease characterized by abnormally high plasma glucose levels, leading to major complications such as diabetic neuropathy, retinopathy, and cardiovascular diseases. The management of blood glucose levels is a critical strategy in the control of diabetes complications. Inhibitors of carbohydrate hydrolyzing enzymes (such as α-glucosidase and α-amylase) have been useful as oral drugs for the control of hyperglycemia, especially in…
Jignesh G. Shah1, Dr. Bharat G. Patel2, Sandip B. Patel1, Ravindra Patel11Department of Pharmacology, Indukaka Ipcowala College of Pharmacy, New Vallabh vidyanagar, Anand, Gujarat, India. 2Institute of Science & Technology for Advanced studies & Research, Vallabh vidyanagar, Anand, Gujarat, India. Pharmacognosy Communications,2012,2,2,34-39DOI: 10.5530/pc.2012.2.5Published:April 2012Type: Research Article ABSTRACT Objective: To evaluate its anti-urolithic potential, the ethanolic extract of seeds of Hordeum vulgare was tested in an animal model of urolithiasis. Materials and Methods: Urolithiasis was induced by the addition of 3% glycolic acid to the normal diet of Wistar albino rats for a period of 42 days. Group I served as a normal control.…
Nithya S, Sumadhuri S, Anbu J, Sumithra MDepartment of Pharmacology, School of Pharmaceutical Sciences, Vels University, Pallavaram, Chennai 600117, India. Pharmacognosy Communications,2012,2,2,40-43DOI: 10.5530/pc.2012.2.6Published:April 2012Type: Research Article ABSTRACT Objective: The aim of the present work was to evaluate the in vitro effect of ginseng on cataract induced by glucose. Materials and Methods: Goat eye lenses were divided into four groups. Group I lenses were incubated in artificial aqueous humor with glucose concentration 5.5 mM (normal control). Group II lenses were incubated with glucose concentration 55 mM (toxic control). Group III and IV lenses incubated with glucose concentration 55 mM were incubated along with ginseng…
Gyanendra Singh4, Swapnil Sharma, Naveen Choudhary3, Sachdev Yadav1, Rajani Chauhan1, and Jaya Dwivedi2 1Deptt. of Pharmacy, Banasthali University-304022, Rajasthan, India. 2Deptt. of Chemistry, Banasthali University,-304022, Rajasthan, India. 3Mandsaur institute of pharmacy, Mandsaur Rajasthan, India. 4Apex institute of pharmacy, sitapura, Jaipur, Rajasthan, India. Pharmacognosy Communications,2012,2,2,44-49DOI: 10.5530/pc.2012.2.7Published:April 2012Type: Research Article ABSTRACT This is aimed to examine radio protective effect of Curcuma longa rhizome extract (CLE) on radiation induced chromosomal aberrations in cancer treatment. The 50% hydroalcoholic extract was used to treat blood sample (taken from a healthy volunteer). In-vitro cytogenic analysis was performed by arresting metaphase using colchicine. The chromosomal aberrations were…
Kalavarasariel Gopinathanpillai Prasanth1*, Eluri Kalpana1, Balasubramaniam Dineshkumar2, Elumalai Monogaran3, Govindharajalu Geetha4, Ramasamy Venkatanarayanan5 1Department of Pharmacology, PSG College of Pharmacy, Coimbatore-04, India. 2Department of Pharmaceutics, PSG College of Pharmacy, Coimbatore-04, India. 3School of Pharmacy, UCSI University, Kula Lumpur, Malaysia. 4Department of Pharmaceutical Analysis, PSG College of Pharmacy, Coimbatore-04, India. 5Department of Pharmacognosy, RVS College of Pharmacy, Coimbatore-04, India. Pharmacognosy Communications,2012,2,2,50-60DOI: 10.5530/pc.2012.2.8Published:April 2012Type: Research Article ABSTRACT Introduction: Obesity is a major factor in causing of atherosclerosis. Tetrahydrocurcumin (THC) may prevent atherosclerosis in high-fat diet-induced hypercholesteremic animals. However, the effect of tetrahydrocurcumin on HMG-CoA reductase and lipoprotein lipase enzymes levels in high-fat diet…
Mohammad Yasir1, Rahul Shrivastava1, Preteek Jain2, Debajyoti Das2 1Department of Bioinformatics, Maulana Azad National Institute of Technology, Bhopal-INDIA. 2Department of Pharmacognosy, Siksha O Anusandhan University, Bhubaneswar-INDIA. Pharmacognosy Communications,2012,2,2,61-66DOI: 10.5530/pc.2012.2.9Published:April 2012Type: Research Article ABSTRACT Introduction: Acacia arabica and Withania coagulans commonly known as babool and paneer phool respectively are used in traditional Indian medicine for treatment of diabetes mellitus. Methods: The hypoglycemic effect of aqueous extracts (hot and cold water) and hydroalcoholic extract of Acacia arabica and Withania coagulans was investigated. Oral administration of a cold water extract of Acacia arabica bark, and a hydroalcoholic extract of Withania coagulans to diabetic and normal rats at a dose of 400 mg/kg…
Dhanabal SP*1, Rahul Jain1, Priyanka Dwarampudi L1, Muruganantham N1, Raghu PS2 1Department of Phytopharmacy and Phytomedicine (TIFAC CORE HD), JSS College of Pharmacy, Rocklands, Ooty, Tamilnadu, India – 643001. 2Department of Pharmaceutical Chemistry, JSS College of Pharmacy, Rocklands, Ooty, Tamilnadu, India – 643001. Pharmacognosy Communications,2012,2,2,67-70DOI: 10.5530/pc.2012.2.10Published:April 2012Type: Research Article ABSTRACT Background: Santolina chamaecyparissus Linn. is used traditionally in Ayurvedic system of medicine in India for the treatment of liver diseases, and as a liver tonic. Methods: The hydroalcoholic extract of Santolina chamaecyparissus Linn. whole plant was tested for its hepatoprotective effect against D-galactosamine induced hepatic damage in rats at a dose of 250°mg/kg. Results: The substantially elevated…
I.E. Cocka,baEnvironmental Futures Centre, Nathan Campus, Griffith University, 170 Kessels Rd, Nathan, Brisbane, Queensland 4111, Australia.bBiomolecular and Physical Sciences, Nathan Campus, Griffith University, 170 Kessels Rd, Nathan, Brisbane, Queensland 4111, Australia Pharmacognosy Communications,2012,2,2,71-77DOI: 10.5530/pc.2012.2.11Published:April 2012Type: Research Letter ABSTRACT Introduction: Many species of Syzygium are known to have antiseptic activity. Australian Syzygium species had roles as traditional bush medicines for Australian Aborigines although their antiseptic potential has not been rigorously studied. Methods: The antimicrobial activity of methanolic extracts of Syzygium australe and Syzygium leuhmannii leaves was investigated by disc diffusion assay and growth time course assay against a panel of bacteria and fungi. Toxicity…
I.E. Cocka,baEnvironmental Futures Centre, Nathan Campus, Griffith University, 170 Kessels Rd, Nathan, Brisbane, Queensland 4111, Australia.bBiomolecular and Physical Sciences, Nathan Campus, Griffith University, 170 Kessels Rd, Nathan, Brisbane, Queensland 4111, Australia Pharmacognosy Communications,2012,2,2,78DOI: 10.5530/pc.2012.2.12Published:April 2012Type: Medicinal Plant Images ABSTRACT Grevillea spp: Grevillea (family Proteaceae) is a genus of approximately 360 species, most of which are native to Australia, although some species are also native to Indonesia, Papua New Guinea and the South Pacific region. Indigenous Australians used some Grevillea species as a food plant and as a medicine. The leaves and bark in particular were used to treat skin sores,…